近代民间年画中的女性及女性美

本文对近代年画中出现的传统女性形象进行了描述与分析,试图通过对视觉形象的剖析来寻找在中国传统文化下,有关女性美的审美传统,同时探究这一传统又以何种视觉形式在极为活跃的市民艺术领域得以传承。     

基于知识管理理论的产品设计与开发

本文基于对知识管理的基本理论的研究,从产品设计与开发的活动出发,在设计层面对知识管理理论进行探讨,并对产品设计与开发中知识管理的流程和各个阶段的相互作用进行了具体的分析。论述了建立面向产品设计的知识管理系统,实现知识共享、知识应用和知识创新,保持设计的创新能力和开发能力,以及如何建立服务于产品设计的知识管理系统。     

基于CORBA综合网络配置管理的设计与实现

CORBA是OMG制定出的一套分布式对象技术标准,其优势在于可以成为分布式异构环境下应用软件开发的统一标准,综合网络管理系统就是一个典型的分布式异构系统.因此,CORBA技术是目前构建综合网管系统一种理想的解决方案.分析了传统网络管理技术的弊端以及CORBA技术应用在网络管理系统的优点,采用基于CORBA的中间件技术、综合网管系统中配置管理接口技术.提出了一种基于CORBA的综合网络配置管理的解决方案,从而利用CORBA的平台无关性,让NMC可以实现统一网络管理任意厂商设备的配置信息,使任意厂商设备能够无缝对接.     

Analysis of biofluids for biomarker research

While many of the developments made in high-throughput proteomics were originally applied to procaryotic and simple eucaryotic organisms, the analysis of biofluids became increasingly important as the prospect of using proteomics to discover novel biomarkers became realized. Biofluids have represented a unique challenge to proteomics as they are often present only in small amounts and, particularly in the cases of serum and plasma, can have protein concentration ranges that differ by ten orders of magnitude. While the discovery of authentic, clinically useful biomarkers in the proteomics era has been lacking, there have been a number of significant developments in the ability to more comprehensively characterize biofluid proteomes. The rapid pace of these developments suggest that the eventual discovery of clinically validate biomarkers using proteomic technologies still has a bright future.     

Three-dimensional reconstruction on PC-Windows platform for evaluation of living donor nephrectomy

Evaluation of renal vasculature was necessary for preoperative donor assessment in living donor kidney transplantation, and the ability to view the vascular imaging in three-dimensional (3D) space should be helpful undoubtedly. Considering the widespread use of personal computer (PC) systems, we aimed to find a handy way to display the anatomy of the renal arterial and venous systems of potential donors on PC-Windows platform. Ten living-related donors were included in this study. Serial computed tomography (CT) images were loaded into Amira 3.1 running on a PC with Windows XP. Following image crop, segmentation and 3D reconstruction, we got the 3D images and the video clips. According to the displays which were confirmed by latter intraoperative findings, eight donors had single renal vessels, one had a left accessory renal artery and one had a right accessory renal artery. This project offered a new approach to evaluate the renal vessel anatomy in living donor kidney transplantation, and it was favorable for accuracy and popularizing.     

代码组件的组合重用是一种新的程序设计范型

本文在描述了程序设计范型的特性之后,详细地介绍了代码组件的组合重用方法,提出并论述了代码组件的组合重用是一种新程序设计范型的观点.本文还详细地描述了这种新程序设计范型的特点,同时也指出了应当解决的一些课题.     

路由协议测试的窗口黑盒模型和多通道的测试方法

路由协议测试中的效率和覆盖率亟待提高,原有通信协议测试理论将被测实现作为黑盒,使得大量可增强控制观察能力的手段无法利用,因此在路由协议测试中以窗口黑盒模型描述被测实现,在测试结构上实现了多通道测试方法,提高了测试效率和测试覆盖率,通过与被测模块交互的其它模块,增强了测试的控制观察能力,测试便的执行时间相比原有方式下降50％;消除或减小了以往不能测试的范围和内容,相应测试例个数增加3倍以上;为目前急需的大规模的路由器测试工作奠定了基础。     

Towards understanding the mechanism of action of the multidrug resistance-linked half-ABC transporter ABCG2: a molecular modeling study

The ATP-binding cassette protein ABCG2 is a member of a broad family of ABC transporters with potential clinical importance as a mediator of multidrug resistance. We carried out a homology and knowledge-based, and mutationally improved molecular modeling study to establish a much needed structural framework for the protein, which could serve as guidance for further genetic, biochemical, and structural analyses. Based on homology with known structures of both full-length and nucleotide-binding domains (NBD) of ABC transporters and structural knowledge of integral membrane proteins, an initial model of ABCG2 was established. Subsequent refinement to conform to the lipophilic index distributions in the transmembrane domain (TMD) and to the results of site-directed mutagenesis experiments led to an improved model. The complete ABCG2 model consists of two identical subunits facing each other in a closed conformation. The dimeric interface in the nucleotide-binding domain (NBD) involves a characteristic nucleotide sandwich and the interface in the TMD consists of the TM helices 1–3 of one subunit and the helices 5 and 6 of the other. The interface between the NBD and the TMD is bridged by the conserved structural motif between TM2 and TM3, the intracellular domain 1 (ICD1), and the terminal β-strand (S6) of the central β-sheet in the NBD. The apparent flexibility of the ICD1 may play a role in transmitting conformational changes from the NBD to the TMD or from the TMD to the NBD.     

Restoring warped document images through 3D shape modeling

Scanning a document page from a thick bound volume often results in two kinds of distortions in the scanned image, i.e., shade along the "spine" of the book and warping in the shade area. In this paper, we propose an efficient restoration method based on the discovery of the 3D shape of a book surface from the shading information in a scanned document image. From a technical point of view, this shape from shading (SFS) problem in real-world environments is characterized by 1) a proximal and moving light source, 2) Lambertian reflection, 3) nonuniform albedo distribution, and 4) document skew. Taking all these factors into account, we first build practical models (consisting of a 3D geometric model and a 3D optical model) for the practical scanning conditions to reconstruct the 3D shape of the book surface. We next restore the scanned document image using this shape based on deshading and dewarping models. Finally, we evaluate the restoration results by comparing our estimated surface shape with the real shape as well as the OCR performance on original and restored document images. The results show that the geometric and photometric distortions are mostly removed and the OCR results are improved markedly.